Sunday, 23 February 2025

ताक (Buttermilk ) पिण्याचे फायदे..........

 ताक हे आयुर्वेद आणि आधुनिक विज्ञान दोन्हीमध्ये पचनासाठी आणि एकूणच आरोग्यासाठी अत्यंत फायदेशीर मानले जाते. त्यातील जिवाणू, जीवनसत्त्वे आणि खनिजे शरीरासाठी उपयुक्त असतात.

१. पचन सुधारते

  • ताकामध्ये प्रोबायोटिक्स (चांगले जिवाणू) असतात, जे पचनसंस्थेला मदत करतात.
  • अपचन, गॅस, अॅसिडिटी यांसारख्या समस्यांवर ताक उपयुक्त आहे.
  • पचनक्रियेला चालना देण्यासाठी जेवणानंतर ताक प्यावे.

२. शरीराला थंडावा देते

  • उन्हाळ्यात ताक पिल्यास शरीरातील उष्णता कमी होते.
  • उन्हामुळे होणाऱ्या निर्जलीकरणापासून (डिहायड्रेशन) संरक्षण मिळते.

३. रोगप्रतिकारशक्ती वाढवते

  • ताकात लॅक्टिक अॅसिड असते, जे शरीरातील चांगल्या जिवाणूंची वाढ करून रोगप्रतिकारशक्ती सुधारते.
  • सर्दी, खोकला आणि संक्रमण टाळण्यासाठी मदत होते.

४. हाडे आणि दात मजबूत होतात

  • ताकामध्ये भरपूर कॅल्शियम आणि फॉस्फरस असते, जे हाडांसाठी आणि दातांसाठी उपयुक्त आहे.
  • हाडे मजबूत राहण्यासाठी नियमित ताकाचे सेवन करावे.

५. हाय ब्लड प्रेशर नियंत्रणात ठेवते

  • संशोधनानुसार, ताकात असलेले जैविक घटक रक्तदाब नियंत्रित करण्यात मदत करतात.
  • हृदयाच्या आरोग्यासाठी ताक उपयुक्त आहे.

६. वजन कमी करण्यास मदत

  • ताक हे कमी कॅलरीयुक्त असून पचनक्रिया सुधारते, त्यामुळे वजन नियंत्रणात राहते.
  • चरबी विरघळवण्यास मदत होते.

७. त्वचा आणि केसांसाठी फायदेशीर

  • ताकामध्ये लॅक्टिक अॅसिड असल्यामुळे त्वचा मऊ आणि चमकदार होते.
  • केसांना पोषण मिळते आणि कोंडा कमी होतो.

८. विषारी पदार्थ बाहेर टाकते (डिटॉक्सिफिकेशन)

  • ताक पिण्यामुळे शरीरातील विषारी घटक बाहेर टाकले जातात आणि लिव्हर निरोगी राहते.

९. मूळव्याध (पाइल्स) आणि जळजळ यासाठी उपयुक्त

  • ताकात हिंग आणि जिरे टाकून प्यायल्यास पचनक्रिया सुधारते आणि गॅस व अपचनासारख्या समस्या दूर होतात.
  • मूळव्याध असलेल्या लोकांनी ताकाचे नियमित सेवन करावे.

१०. मधुमेहासाठी फायदेशीर

  • ताकाच्या नियमित सेवनाने रक्तातील साखर नियंत्रित राहते आणि मधुमेहाच्या रुग्णांसाठी फायदेशीर ठरते.

कसे प्यावे?

  • साधे ताक किंवा त्यात जिरे, हिंग, आले, कोथिंबीर टाकून प्यायल्यास अधिक फायदेशीर ठरते.
  • शक्यतो जेवणानंतर किंवा दुपारी ताक प्यावे.

ताक हे नैसर्गिक आणि आरोग्यासाठी लाभदायक पेय आहे. रोजच्या आहारात समाविष्ट करून त्याचा संपूर्ण फायदा घ्यावा!

 

Thursday, 23 January 2025

Guillain-Barré Syndrome (GBS):

 Symptoms

Guillain-Barré Syndrome (GBS) is a rare neurological disorder in which the body’s immune system attacks the peripheral nerves. The symptoms of GBS often progress rapidly and can vary in severity. Below is a detailed description of the key symptoms:

1. Initial Symptoms

  • Tingling Sensation or Numbness:
    • Begins in the extremities, such as fingers, toes, wrists, and ankles.
    • May feel like "pins and needles" and can spread upwards in the body.
  • Weakness in the Legs:
    • Initial muscle weakness often starts in the lower limbs, making walking or climbing stairs difficult.
    • Weakness may be mild or severe, leading to immobility.

2. Progressive Symptoms

  • Ascending Muscle Weakness:
    • Weakness spreads from the legs to the upper body, arms, and sometimes the facial muscles.
    • In severe cases, it can progress to the respiratory muscles, causing difficulty in breathing.
  • Loss of Reflexes:
    • Reflexes, such as knee-jerk, are diminished or absent.
  • Difficulty with Eye Movements or Facial Expressions:
    • Weakness in facial muscles can result in problems with blinking, smiling, or chewing.
    • Eye movement abnormalities, like double vision, may occur.

3. Autonomic Nervous System Symptoms

  • Blood Pressure Fluctuations:
    • May experience low or high blood pressure.
  • Heart Rate Abnormalities:
    • Irregular heartbeat (arrhythmias) or rapid heart rate (tachycardia).
  • Sweating or Temperature Regulation Issues:
    • Abnormal sweating or difficulty maintaining body temperature.

4. Sensory Symptoms

  • Pain:
    • Severe nerve pain is common, often described as a burning, aching, or stabbing sensation.
    • Pain may worsen at night.
  • Impaired Sensation:
    • Numbness or loss of sensation in affected areas.

5. Severe or Life-Threatening Symptoms

  • Respiratory Failure:
    • Weakness of the diaphragm and respiratory muscles can lead to difficulty breathing and require mechanical ventilation.
  • Paralysis:
    • In severe cases, paralysis may occur, affecting the ability to move, speak, or perform basic functions.
  • Difficulty Swallowing (Dysphagia):
    • Can lead to choking or aspiration of food and fluids.

6. Chronic and Long-Term Symptoms (in rare cases of incomplete recovery or chronic inflammatory demyelinating polyneuropathy - CIDP):

  • Persistent weakness or fatigue.
  • Residual nerve damage leading to reduced coordination or sensory issues.

Progression and Timeline

  • Symptoms usually develop over a few days to weeks.
  • The progression typically peaks within 2-4 weeks, followed by a plateau phase, and then recovery begins.

When to Seek Medical Attention

  • Seek immediate medical care if you experience rapid onset of muscle weakness, difficulty breathing, or swallowing, as GBS can be life-threatening without timely treatment.

Guillain-Barré Syndrome requires urgent medical attention as its symptoms can escalate quickly, affecting the ability to breathe and move. With prompt treatment, including plasmapheresis or intravenous immunoglobulin (IVIG), most patients recover, although some may have lasting effects.




Wednesday, 9 October 2024

The Nobel Prize in Chemistry 2024

 N


obel Prize in Chemistry 2024 is about pro￾teins, life’s ingenious chemical tools. David Baker 

has succeeded with the almost impossible feat 

of building entirely new kinds of proteins. Demis 

Hassabis and John Jumper have developed an AI 

model to solve a 50-year-old problem: predicting 

proteins’ complex structures. These discoveries 

hold enormous potential. 

The diversity of life testifes to proteins’ amazing capacity 

as chemical tools. They control and drive all the chemi￾cal reactions that together are the basis of life. Proteins 

also function as hormones, signal substances, antibodies 

and the building blocks of diferent tissues. 

“One of the discoveries being recognised this year 

concerns the construction of spectacular proteins. The 

other is about fulflling a 50-year-old dream: predicting 

protein structures from their amino acid sequences. 

Both of these discoveries open up vast possibilities,” 

says Heiner Linke, Chair of the Nobel Committee for 

Chemistry.

Proteins generally consist of 20 diferent amino acids, 

which can be described as life’s building blocks. In 2003, 

David Baker succeeded in using these blocks to design 

a new protein that was unlike any other protein. Since 

then, his research group has produced one imaginative 

protein creation after another, including proteins that 

can be used as pharmaceuticals, vaccines, nanomaterials 

and tiny sensors. 

The second discovery concerns the prediction of protein 

structures. In proteins, amino acids are linked together 

in long strings that fold up to make a three-dimensional 

structure, which is decisive for the protein’s function. 

Since the 1970s, researchers had tried to predict protein 

structures from amino acid sequences, but this was 

notoriously difcult. However, four years ago, there was 

a stunning breakthrough.

In 2020, Demis Hassabis and John Jumper presented an 

AI model called AlphaFold2. With its help, they have 

been able to predict the structure of virtually all the 200 

million proteins that researchers have identifed. Since 

their breakthrough, AlphaFold2 has been used by more 

than two million people from 190 countries. Among 

a myriad of scientifc applications, researchers can 

now better understand antibiotic resistance and create 

images of enzymes that can decompose plastic.

Life could not exist without proteins. That we can now 

predict protein structures and design our own proteins 

Monday, 7 October 2024

Nobel Prize 2024 in medicine for their groundbreaking discovery of microRNA and its crucial role in post-transcriptional gene regulation.

 

Tiny RNAs with profound physiological importance

Gene regulation by microRNA, first revealed by Ambros and Ruvkun, has been at work

for hundreds of millions of years. This mechanism has enabled the evolution of

increasingly complex organisms. We know from genetic research that cells and tissues

do not develop normally without microRNAs. Abnormal regulation by microRNA can

contribute to cancer, and mutations in genes coding for microRNAs have been found in

humans, causing conditions such as congenital hearing loss, eye and skeletal disorders.

Mutations in one of the proteins required for microRNA production result in the DICER1

syndrome, a rare but severe syndrome linked to cancer in various organs and tissues.

Ambros and Ruvkun’s seminal discovery in the small worm C. elegans was unexpected,

and revealed a new dimension to gene regulation, essential for all complex life form.